Enabling the collaborative research in Precision Health that is instrumental in the transition to preventative medicine

Tom Bashford

Operations Research & Management Science  Anaesthesia  

Dr Bashford's principal academic interest is in developing a systems understanding of interventions to improve peri-operative care in low income settings, working closely with the NIHR Global Health Research Group on Neurotrauma. His global health experience includes working with VSO and Lifebox Foundation in Ethiopia, contributing to the Cambridge-Yangon Trauma Intervention Project in Myanmar, and the Uganda Cambridge Partnership.

neurotrauma  perioperative medicine  anaesthesia  system design  health system  

Carol Brayne

Environmental & Occupational Health  Medicine  

Prof Brayne is co-director of Cambridge Public Health, and is a public health clinical academic whose research career has focused on older people's health and brain ageing in populations, including biobanking. She has led the largest multi-centre study of cognition and dementia in the UK. She has also worked in areas of neurological and neuropsychiatric epidemiology such as the epidemiology of autism spectrum disorders, psychiatric disorders in mid-life.

health of elderly  dementia in population  

Andrew McCaskie

Orthopedics  Medicine  

Prof McCaskie is an orthopaedic surgeon with an interest in lower limb surgery. His research aims to develop innovative solutions, particularly regenerative, for patient benefit in musculoskeletal disease. The research encompasses a greater understanding of the causes of musculoskeletal disease and the mechanisms of action of therapy.

regenerative innovation solutions for musculoskeletal disease  lower limb surgery  

Martin Bennett

Cardiovascular Research  Imaging  

Prof Bennett studies the regulation of cell accumulation and interactions in vascular disease, using both human and mouse cells in vitro and models of atherosclerosis with genetic manipulation. He also has a major interest in vulnerable plaque imaging in patients using both invasive and non-invasive modalities.

regulation of cell accumulation and interactions in vascular disease  plaque imaging  

Clare Bryant

Immunology  Medicine  

Prof Bryant's research employs multidisciplinary approaches to understand how bacteria are detected by the host through Pattern Recognition Receptors (PRRs), and how PRR recognition of allergen proteins or toxic proteins produced by patients link to chronic inflammatory diseases such as allergies and Alzheimer’s

effector mechanisms  immunological recognition  

Rebecca Fitzgerald

Oncology  Medicine  

Prof Fitzgerald's group focuses on oesophageal and gastric cancer by understanding the underlying clinical, genetic and cell environmental factors, developing and evaluating new diagnostic tools to identify patients' cancer development risk, and improving the molecular characterisation of oesophago-gastric cancer to inform patient management.

oesophageal/gastric cancer  early detection  public health  clinical trials  

Andres Floto

Medicine  Immunology  

Prof Floto's research is focused on understanding how immune cells interact with bacteria, how intracellular killing and inflammation are regulated and sometimes subverted during infection, how population-level whole genome sequencing can be used to reveal biology of bacterial infection, and how therapeutic enhancement of cell-autonomous immunity may provide novel strategies to treat multi drug resistant pathogens.

polulation level genome sequencing  bacteria interaction  immune cell  

Patrick Maxwell

Nephrology  Medicine  

Prof Maxwell, a clinician scientist, has been centrally involved in a series of discoveries that have revealed how changes in oxygenation are sensed, and how genetic alterations cause kidney disease. It has had a major impact on the understanding of tumour biology, anaemia, and inflammatory disorders.

tumor biology  infflammatory disorder  biomedical/clinical research  nephrology  

David Menon

Anaesthesia  Medicine  

Prof Menon’s research interests include neurocritical care, secondary brain injury, neuroinflammation, and metabolic imaging of acute brain injury. He has also published on the physiology of coma and the vegetative state, and on mechanisms of anaesthetic action in the brain.

neuroinflammation  metabolic imaging  secondary brain injury  neurocritical care  

James Rudd

Cardiovascular Research  Medicine  

Professor Rudd's research interests are in vascular imaging, using CT, MRI and nuclear methods. He applies biomechanical, mathematical methods and AI to refine risk on top of imaging and demographic factors. He works across disease states, including stroke, ischaemic heart disease, peripheral vascular disease, aortic aneurysm, rheumatoid arthritis and pulmonary hypertension. He also has expertise in electronic healthcare record research and is deputy chief clinical information officer at Addenbrooke's Hospital.

imaging  cardiovascular  pathophysiology  AI  bioengineering  HER  

Hitesh Sanganee

Respiratory System  Medicine  

Dr Sanganee joined AstraZeneca as a Medicinal Chemist conducting research within respiratory & inflammation related disease areas and has led teams to successful milestone transitions in all phases of drug discovery. He then moved on to become a candidate drug Associate Director. He currently leads the ‘Emerging innovations’ group. Promotion of entrepreneurial activity within and outside of AZ and bringing emerging innovations into AZ.

inflammation  innovation  drug discovery  

Jason Tarkin

Cardiovascular Research  Medicine  

Dr Tarkin's current research programme aims to examine potential clinical translational applications of somatostatin receptor PET/MRI as a marker of inflammation for studying disease mechanisms, use in drug discovery and guiding novel therapies in high-risk patients with cardiovascular disease and large vessel vasculitis.

drug discovery  inflammation  cardiovascular  medical applications  

Brian Tom

Biostatics  Medicine  

Dr Tom is a research statistician at the Medical Research Council Biostatistics Unit. His current research interest includes causal inference, chronic disease epidemiology (in particular related to inflammatory arthritis), dynamic graphical modelling of stochastic processes, efficiency, modelling of longitudinal and correlated data, multi-state models and survival data, stratified medicine.

infllammatory arthritis  chronic disease  stratified medince  modelling